Resistance in tuberculosis: what do we know and where can we go?

نویسندگان

  • Keith D. Green
  • Sylvie Garneau-Tsodikova
چکیده

Tuberculosis (TB) has become a worldwide threat, mainly due to the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (Mtb). This mini-review is focused on the various mechanisms of resistance to the currently available anti-TB drugs and provides perspective on novel strategies and lead scaffolds/compounds aimed at inhibiting/overcoming these resistance mechanisms.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2013